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Why do parasites harm their hosts? The study asked if parasites could evolve virulence by balancing the benefits of using their hosts to transmit disease and the costs of possible host death due to their effects. Using the monarch-OE system, researchers compared the effects of # of parasites on a host to mating success, lifespan, lifetime reproductive success, and infection rates in monarch butterflies. Among their results, they found that higher #s of parasites led to lower proportions of monarchs surviving to adulthood (graph shown on left, below). They also found females monarchs that were more infected passed along higher amounts of parasites to eggs and on milkweed plants. The greater the # of spores on the plants, the more likely the larvae were infected (graph shown on right, below). |
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2. Host plants affect parasite replication and virulence
Fall 07 - A study from the lab shows how the infection severity of OE and effects on monarchs depends on what milkweed species the larvae eat! The study was by Jaap de Roode, Amy Pedersen, Mark Hunter, and Sonia Altizer and was published in the Journal of Animal Ecology. Click here to view the pdf version of the paper.
Highlights from the study:
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The study involved rearing monarch larvae on either swamp milkweed (Asclepias incarnata) or tropical milkweed (Asclepias currasavica), which both differ in cardenolide (milkweed toxin) content (left graph). Then the larvae were experimentally inoculated with OE and reared to adulthood. Their spore loads and survival were recorded. The results showed that monarchs reared on tropical milkweed lived longer when infected and had lower spore loads during infections. |
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3. Parasites replicate rapidly and reduce monarch survival
Spring 07 - A study from the Altizer lab shows how the severity of OE infection influences the biology of monarchs. The study was by Jaap de Roode, Laura Gold and Sonia Altizer and was published in the journal, Parasitology. Click here to view the pdf version of the paper.
Highlights from the study:
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Since the study involved examining variation in infection levels, Jaap had to devise a method of experimentally infecting larvae with single spores! He ended up making super-tiny glass rods (left) with which he could pick up and transfer single spores and place them on monarch eggs (below)! | ||
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4. Parasites hinder monarch flight performance
Spring 05 - A study from the Altizer lab on the effects of OE on monarch butterfly flight is released, with lots of press (below)! The study was by Catherine Bradley and Sonia Altizer and was published in the journal, Ecology Letters. Click here to view a pdf version of this paper.
Highlights from the study:
The objective of the study was to determine if monarchs infected with OE were capable of flying equally as well as uninfected ones. To do this, the team solicited the help of the Emory University Physics dept, who designed a 'butterfly treadmill' (or flightmill, pictured right) to test the monarchs. Infected and uninfected adult monarchs were tested using this apparatus, which measured their flight speed and endurance. The results showed that infected monarchs were not able to fly as well as uninfected - their speed was lower (below) and their endurance was also lower. These results have large implications for monarch migration. ![]() |
![]() Flight mill designed by Horace Dale to test flight endurance of healthy and parasitized monarch butterflies |
![]() Horace Dale, Sonia Altizer and Catherine Bradley |
Below are several articles in the popular press that were written about this study:
By Stéphan Reebs in the October 2005 issue of Natural History magazine:
In the American Society of Microbiologists' Newsletter, 2005:

This article was written by our very own Jaap de Roode:

Other articles...
Emory Press Release: Monarch Health Tied to Migration
Highlighted in Science Editor's Choice section [PDF]
Release on ScienceDaily.com
Earthwatch Radio: Migratory Immunity
BBC Wildlife: Butterfly Purges Travel Bug
5. Prevalence of OE varies among global monarch populations
Research in our lab and others has revealed that the OE parasite infects populations of monarchs differently around the globe. Although much of our research is aimed at identifying the reasons for this variation, we do know what proportion of individuals is infected from North American populations. Below is the variation in prevalence (percent of individuals with HEAVY OE infections) in the three known North American monarch populations. The prevalence is lowest in the eastern monarch population (which migrates the longest distance - shown by arrows), and highest in the non-migratory South Forida population. Anecdotal evidence suggests that a high proportion of monarchs from Hawaii are heavily infected. Click here to view the original paper with this data.
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![]() These prevalence estimates have stayed the same through time as indicated by the chart above. In this chart, yellow points represent eastern monarchs, orange represents western, and green represents monarchs from South Florida. |
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Global population prevalence of OE varies according to the migration tendency of the population. The monarch population in eastern N. America (that has the longest migration) has the lowest prevalence of OE. The populations with no or little migration have the highest prevalence. |
Strength in numbers: Parasite transmission & virulence in monarch butterflies
Genetic and Environmental Determinants of Host Susceptibility and Parasite Infection in Monarch Butterflies
Effects of parasite infection on the flight performance of monarch butterflies (Danaus plexippus)
Other citizen science websites with monarchs
Monarch Larva Monitoring Project began in 1997 at the University of Minnesota. It involves citizens in collecting data that will help to explain the distribution and abundance patterns of monarch butterflies in North America.
Journey North helps students study wildlife migration and seasonal change. They track the coming of spring through the migration patterns of monarch butterflies, robins, hummingbirds, whooping cranes, gray whales, bald eagles— and other birds and mammals; the budding of plants; changing sunlight; and other natural events.
Monarch Migratory Association of America: A network of existing monarch migration projects that all focus on : counting the annual numbers of monarchs that migrate though specific sites in North America.
Monarchs Across Georgia: A collaboration of teachers, students, families, communities, businesses and others, all working together to study Monarch butterflies and restore butterfly habitat across Georgia.