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Publications: Jeff Fisher

  • Keys, Deborah, Irvin Schultz, Deirdre Mahle, Jeffrey Fisher. (2004). "A Quantitative Description of Suicide Inhibition of Dichloroacetic Acid in Rats and Mice." Toxicological Science 82, 381-292.
  • Dixon, A., D. Delinsky, J.V. Bruckner, J.W. Fisher, M. Bartlett. (2004). "Analysis of Dichloroacetic Acid in Drinking Water by Ion Exchange HILIC-LC/MS/MS." Journal of Liquid Chromatography & Related Technologies, Vol. 27, No. 15, pp. 2343-2355.
  • Bruckner, J.V., D. Keys, J.W. Fisher. (2004). "The Acute Exposure Guideline Level (AEGL) Program: Applications of Physiologically Based Pharmacokinetic Modeling." Journal of Toxicology and Environmental Health, Part A, 67:621-634.
  • Fisher, J., M. Lumpkin, J. Boyd, D. Mahle, J.V. Bruckner, H.A. El-Masri. (2003). "PBPK modeling of the metabolic interactions of carbon tetrachloride and tetrachloroethylene in B6C3F1 mice." Environmental Toxicology and Pharmacology, 16, 93-105.
  • Keys, Deborah, James Bruckner, Srinivasa Muralidhara, and Jeffrey Fisher. (2003). "Tissue Dosimetry Expansion and Cross-Validation of Rat and Mouse Physiologically Based Pharmacokinetic Models for Trichloroethylene." Toxicologyical Sciences, 76, 35-50.
  • Lumpkin, Michael, James Bruckner, Jerry Campbell, Cham Dallas, Catherine White, and Jeffrey Fisher. (2003) "Plasma Binding of Trichloroacetic Acid in Mice, Rats, and Humans under Cancer Bioassay and Environmental Exposure Conditions." Drug Metabolism and Disposition, Vol 31, 1203-1207.
  • Merrill, Elaine A., Rebecca A. Clewell, Jeffery M. Gearheart, Peter J. Robinson, Teresa R. Sterner, Kyung O. Yu, David R. Mattie and Jeffrey W. Fisher. (2003) PBPK Predictions of Perchlorate Distribution and Its Effect on Thyroid Uptake of Radioiodide in the Male Rat. Toxicological Sciences, 73, 256-269.
  • Clewell, Rebecca A., Elaine A. Merrill, Kyung O. Yu, Deirdre A. Mahle, Teresa R. Sterner, David R. Mattie, Peter J. Robinson, Jeffery W. Fisher, and Jeffery M. Gearhart. (2003) Predicting Fetal Perchlorate Dose and Inhibition  of Iodide Kinetics during Gestation: A Physiologically-Based Pharmacokinetic Analysis of Perchlorate and Iodide Kinetics in the Rat. Toxicological Sciences, 73, 235-255.
  • Sundberg, S. E., J. Jackson Ellington, John J. Evans, Deborah A. Keys and Jeffrey W. Fisher. (2003) Accumulation of perchlorate in tobacco plants: development of a plant kinetic model. Journal of Environmental Monitoring, 5, 505-512.
  • Fisher, Jeffrey W. (2003) PBPK Modeling Advances Understanding of D4 Pharmacokinetics. Toxicological Highlight, Toxicological Sciences 72, 1-2.
  • Narayanan, L., G. W. Buttler G. W. , K. O. Yu, D. R. Mattie, and J. W. Fisher. (2003) Sensitive High- Performance Liquid Chromatography Method for the Determination of Low Levels of Perchlorate in Biological Samples. Journal of Chromatography B, 788, 393-399.
  • Mahle, Deirdre. A., Kyung O. Yu, Latha Narayanan, David R. Mattie and Jeffrey W. Fisher. (2003) Changes in Cross-Fostered Sprague-Dawley Rat Litters Exposed to Perchlorate. International Journal of Toxicology 22, 87-94.
  • Kyung O. Yu, Latha Narayanan, David R. Mattie, Richard J. Godfrey, Paula N. Todd, Teresa R. Sterner, Deirdre A. Mahle, Michael H. Lumpkin and Jeffrey W. Fisher. (2002) The Pharmacokinetics of Perchlorate and Its Effect on the Hypothalamus/Pituitary-Thyroid Axis in the Male Rat.  Toxicol. Appl. Pharmacol.,182 , 146-159.
  • Fisher, J. W. , S. R. Channel, J. S. Eggers, P. D. Johnson, K. L. MacMahon, C. D. Goodyear, G. L. Sudberry, D. A. Warren, J. R. Latendresse, and L. J. Graeter. (2001) Trichloroethylene, Trichloroacetic Acid, and Dichloroacetic Acid:  Do they Affect Fetal Rat Heart Development? International J. Toxicology 20 , 1-11.
  • Dorman, D. C., et al. (2001). "Methods to identify and characterize developmental neurotoxicity for human health risk assessment. III: pharmacokinetic and pharmacodynamic considerations." Environ Health Perspect 109 Suppl 1: 101-11.Fisher, J. W., et al. (2001). "Trichloroethylene, trichloroacetic acid, and dichloroacetic acid: do they affect fetal rat heart development?" Int J Toxicol 20(5): 257-67.
  • Fisher, J. W. (2000). "Physiologically based pharmacokinetic models for trichloroethylene and its oxidative metabolites." Environ Health Perspect 108 Suppl 2: 265-73.
  • Fisher, J. W., D. C. Dorman, M. A. Medinsky, F. Welsch and R. B. Conolly (2000). "Analysis of respiratory exchange of methanol in the lung of the monkey using a physiological model." Toxicol Sci 53(2): 185-93.
  • Fisher, J. W., P. Todd, D. Mattie, D. Godfrey, L. Narayanan and K. Yu (2000). "Preliminary Development of a Physiological Model for Perchlorate in the Adult Rat: A framework for further studies." Drug and Chemical Toxicology 23: 243-258.
  • Lash, L. H., J. W. Fisher, J. C. Lipscomb and J. C. Parker (2000). "Metabolism of trichloroethylene." Environ Health Perspect 108 Suppl 2: 177-200.
  • Greenberg, M. S., G. A. Burton and J. W. Fisher (1999). "Physiologically based pharmacokinetic modeling of inhaled trichloroethylene and its oxidative metabolites in B6C3F1 mice." Toxicol Appl Pharmacol 154(3): 264-78.
  • Lash, L. H., D. A. Putt, W. T. Brashear, R. Abbas, J. C. Parker and J. W. Fisher (1999). "Identification of S-(1,2-dichlorovinyl)glutathione in the blood of human volunteers exposed to trichloroethylene." J Toxicol Environ Health A 56(1): 1-21.
  • Narayanan, L., A. P. Moghaddam, A. G. Taylor, G. L. Sudberry and J. W. Fisher (1999). "Sensitive high-performance liquid chromatography method for the simultaneous determination of low levels of dichloroacetic acid and its metabolites in blood and urine." J Chromatogr B Biomed Sci Appl 729(1-2): 271-7.
  • Brown, E. A., M. L. Shelley and J. W. Fisher (1998). "A Pharmokinetic study of Occupational and Envitonmental Benzene Exposure with regaed to Gender." Risk Analysis 18: 205-213.
  • Fisher, J. W., D. Mahle and R. Abbas (1998). "A human physiologically based pharmacokinetic model for trichloroethylene and its metabolites, trichloroacetic acid and free trichloroethanol." Toxicol Appl Pharmacol 152(2): 339-59.
  • Lipscomb, J. C., J. W. Fisher, P. D. Confer and J. Z. Byczkowski (1998). "In vitro to in vivo extrapolation for trichloroethylene metabolism in humans." Toxicol Appl Pharmacol 152(2): 376-87.
  • Pleil, J. D., J. W. Fisher and A. B. Lindstrom (1998). "Trichloroethene levels in human blood and exhaled breath from controlled inhalation exposure." Environ Health Perspect 106(9): 573-80.
  • Stenner, R. D., J. L. Merdink, J. W. Fisher and R. J. Bull (1998). "Physiologically-based pharmacokinetic model for trichloroethylene considering enterohepatic recirculation of major metabolites." Risk Anal 18(3): 261-9.
  • Abbas, R. and J. W. Fisher (1997). "A physiologically based pharmacokinetic model for trichloroethylene and its metabolites, chloral hydrate, trichloroacetate, dichloroacetate, trichloroethanol, and trichloroethanol glucuronide in B6C3F1 mice." Toxicol Appl Pharmacol 147(1): 15-30.
  • Fisher, J. W., D. Mahle, L. Bankston, R. Greene and J. Gerahart (1997). "Lactational Transfer of Volatile Chemicals in Breast Milk." American Industrial Hygiene Association Journal 58: 425-431.
  • Maull, E. A., V. J. Cogliano, C. S. Scott, H. A. Barton, J. W. Fisher, M.Greenberg, L. Rhomberg and S. P. Sorgen (1997). "Trichloroethylene health risk assessment: a new and improved process." Drug Chem Toxicol 20(4): 427-42.
  • Moghaddam, A. P., R. Abbas, J. W. Fisher and J. C. Lipscomb (1997). "The role of mouse intestinal microflora in the metabolism of trichloroethylene, an in vivo study." Hum Exp Toxicol 16(11): 629-35.
  • Staats, D. A., D. Mattie and J. W. Fisher (1997). "Risk Factors for Petroleum Products and Long Chain Hydrocarbons." Human and Ecological Risk Assessment 3: 659-681.
  • Yu, K. O., J. W. Fisher, G. A. Burton, Jr. and D. E. Tillitt (1997). "Carrier effects of dosing the H4IIE cells with 3,3',4,4'-tetrachlorobiphenyl (PCB77) in dimethyl sulfoxide or isooctane." Chemosphere 35(4): 895-904.
  • Abbas, R. R., C. S. Seckel, J. K. Kidney and J. W. Fisher (1996). "Pharmacokinetic analysis of chloral hydrate and its metabolism in B6C3F1 mice." Drug Metab Dispos 24(12): 1340-6.
  • Moghaddam, A. P., R. Abbas, J. W. Fisher, S. Stavrou and J. C. Lipscomb (1996). "Formation of dichloroacetic acid by rat and mouse gut microflora, an in vitro study." Biochem Biophys Res Commun 228(2): 639-45.
  • Yu, K. O., D. E. Tillitt, J. Z. Byczkowski, G. A. Burton, Jr., S. R. Channel, J. M. Drerup, C. D. Flemming and J. W. Fisher (1996). "In vivo/in vitro comparison of the pharmacokinetics and pharmacodynamics of 3,3',4,4'-tetrachlorobiphenyl (PCB77)." Toxicol Appl Pharmacol 141(2): 434-8.
  • Cronin, W. J. t., E. J. Oswald, M. L. Shelley, J. W. Fisher and C. D. Flemming (1995). "A trichloroethylene risk assessment using a Monte Carlo analysis of parameter uncertainty in conjunction with physiologically-based pharmacokinetic modeling." Risk Anal 15(5): 555-65.
  • Mattie, D. R., G. D. Bates, Jr., G. W. Jepson, J. W. Fisher and J. N. McDougal (1994). "Determination of skin:air partition coefficients for volatile chemicals: experimental method and applications." Fundam Appl Toxicol 22(1): 51-7.
  • Allen, B. C. and J. W. Fisher (1993). "Pharmacokinetic modeling oftrichloroethylene and trichloroacetic acid in humans." Risk Anal 13(1): 71-86.
  • Fisher, J. W. (1993). "Estimating the risks of liver and lung cancer in humans exposed to trichloroethylene using a physiological model." Toxicol Lett 68(1-2): 127-9.
  • Fisher, J. W. and B. C. Allen (1993). "Evaluating the risk of liver cancer in humans exposed to trichloroethylene using physiological models." Risk Anal 13(1): 87-95.
  • Fisher, J. W., M. L. Gargas, B. C. Allen and M. E. Andersen (1991). "Physiologically based pharmacokinetic modeling with trichloroethylene and its metabolite, trichloroacetic acid, in the rat and mouse." Toxicol Appl Pharmacol 109(2): 183-95.
  • Staats, D. A., J. W. Fisher and R. B. Connolly (1991). "Gastrointestinal absorption of xenobiotics in physiologically based pharmacokinetic models. A two-compartment description." Drug Metab Dispos 19(1): 144-8.
  • Fisher, J. W., T. A. Whittaker, D. H. Taylor, H. J. Clewell, 3rd and M. E. Andersen (1990). "Physiologically based pharmacokinetic modeling of the lactating rat and nursing pup: a multiroute exposure model for trichloroethylene and its metabolite, trichloroacetic acid." Toxicol Appl Pharmacol 102(3): 497-513.
  • Fisher, J. W., T. A. Whittaker, D. H. Taylor, H. J. Clewell, 3rd and M. E. Andersen (1989). "Physiologically based pharmacokinetic modeling of the pregnant rat: a multiroute exposure model for trichloroethylene and its metabolite, trichloroacetic acid." Toxicol Appl Pharmacol 99(3): 395-414.
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